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  • The Concept of Optical Tweezers In Cell Biology

    Because of the different refractive index of a cell membrane compared to the bathing solution, it will tend to refract a laser beam impinging on it. Consider the illustration below, in the left side of the figure, with a parallel laser beam impinging on the left side of the cell, the cell is seen to…

  • What is Electroporation?

    Electroporation is a technique that utilizes intense pulses of electricity to ‘punch’ holes in cell membranes. These holes or pores last for a few of milliseconds and are approximately 40 nm in diameter.  This size is sufficient to permit macromolecules such as genes, drugs, metabolites, antibodies or molecular probes to permeate the membrane. The typical…

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